Ingredients (per daily dose = 2 sprays)
- – Melatonin 00 mg
- – Griffonia simplicifolia seeds dry extract (titrated 20% 5-HTP) 1.40 mg of which 5-HTP 28 mg
- J- ujube (Ziziphus jujuba Mill.) seeds dry extract (titrated 2% triterpene saponins) 0.28 mg of which Triterpene Saponins 60 mcg
Pharmacological Properties
- – Fast sublingual absorption: Bypasses hepatic first-pass metabolism, achieving high bioavailability and rapid onset (peak within ~1 hour).
- – Immediate effect: Acts directly on melatonin receptors to synchronize circadian rhythm and shorten sleep latency.
- – Does not affect vigilance: Maintains normal alertness upon waking.
- – Suitable for children and during pregnancy or breastfeeding.
Clinical Indications
MELACRON® is recommended for managing:
- – Sleep disorders caused by:
- 1- Stress and poor lifestyle habit
- 2- Anxiety and mood disturbances
- 3- Jet-lag or delayed sleep onset
- – Situations requiring rapid sleep induction without affecting daytime alertness
Direction
- – Dose: 2 nebulizations per day, sublingually, In the evening, just before bedtime
- – Shake well before use