Cistidep sachets

Ingredients ( per one sachet)

– Inulin   1.6 g

– D-mannose (from birch, Betula pendula Roth., bark) 500 mg

– CystiCran™40 – Cranberry (Vaccinium macrocarpon Aiton) fruits d.e.,135 mg titrated to 40%  proanthocyanidins 54 mg

– Vitamin C 120 mg

– Pido-Zinc® (Zinc pidolate) 11.2

– Berryvin™ – standardized dry extract of mixed fruits: 20 mg

  • Fragaria ananassa (strawberry)
  • Vaccinium myrtillus (bilberry)
  • Malpighia glabra (acerola)
  • Rubus fruticosus (blackberry)
  • Vaccinium macrocarpon (cranberry)
  • Vitis vinifera (grape)
  • Punica granatum (pomegranate

Properties

1. Defensive & Anti-Adhesive Action

  • Cranberry (Proanthocyanidins) and D-Mannose act synergistically to prevent E. coli adhesion to bladder and urethral walls.

  • Facilitate detachment of bacteria already adhering to epithelial cells, promoting elimination through urine.

  • Mechanism: PACs bind fimbriae adhesins of E. coli, while D-Mannose acts as a competitive inhibitor at glycoprotein receptors.

2. Antioxidant Action

  • Berryvin™ (polyphenols, anthocyanins, ellagic acid) + Vitamin C form a potent antioxidant system.

  • Neutralizes free radicals produced during infection and protects mucosal cells from oxidative damage.

  • Reduces inflammation and strengthens mucosal resistance to recurrent infections.

3. Immunomodulating Action

  • Inulin stimulates the alternative complement pathway, increasing white blood cell activity and immune defense against bacteria and viruses.

  • Pido-Zinc® ensures high zinc absorption, exerting immunostimulant and anti-radical actions.

4. Repairing & Reconstructive Action

  • D-Mannose supports the restoration of glycosaminoglycan (GAG) layers of bladder and vaginal mucosa, strengthening mucosal defense and reducing recurrence.

Indications

Cistidep® is suitable for:

  1. Prevention and treatment of urinary tract infections (UTIs), Especially cystitis and urethritis
  2. Recurrent or chronic cystitis
  3. Post-antibiotic mucosal protection
  4. Prevention of infection recurrence in sexually active women or those with postmenopausal atrophy
  5. Supportive therapy alongside antibiotic or antiseptic treatment

Directions

Acute Phase:

  • 1 sachet twice daily for 8 days

    • Preferably in the morning (on waking) and evening (after dinner) on an empty bladder

Prevention of Relapse:

  • 1 sachet daily for 8 days each month

    • Repeat for 4 consecutive months

    • Take in the evening after dinner, on an empty bladder

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